Structure of PDB 6evl Chain A Binding Site BS01

Receptor Information
>6evl Chain A (length=94) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATTTKSQVLDY
LSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQLLEE
Ligand information
Ligand IDGLY
InChIInChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChIKeyDHMQDGOQFOQNFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C(=O)O)N
CACTVS 3.341NCC(O)=O
ACDLabs 10.04O=C(O)CN
FormulaC2 H5 N O2
NameGLYCINE
ChEMBLCHEMBL773
DrugBankDB00145
ZINCZINC000004658552
PDB chain6evl Chain A Residue 303 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6evl Structural enzymology binding studies of the peptide-substrate-binding domain of human collagen prolyl 4-hydroxylase (type-II): High affinity peptides have a PxGP sequence motif.
Resolution1.87 Å
Binding residue
(original residue number in PDB)		D192 Y193
Binding residue
(residue number reindexed from 1)		D49 Y50
Annotation score2
Enzymatic activity
Enzyme Commision number 1.14.11.2: procollagen-proline 4-dioxygenase.
External links
PDB RCSB:6evl, PDBe:6evl, PDBj:6evl
PDBsum6evl
PubMed30168208
UniProtO15460|P4HA2_HUMAN Prolyl 4-hydroxylase subunit alpha-2 (Gene Name=P4HA2)

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