Structure of PDB 6euf Chain A Binding Site BS01

Receptor Information
>6euf Chain A (length=472) Species: 226186 (Bacteroides thetaiotaomicron VPI-5482) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QNTQISPGVLWNDIDGEQINAHGGCVVYEKGTYYWFGEDRTGFKSNGVSC
YQSKDLYNWKRLGLSMKTTGEAREDMNDISQGRLFERPKVIYNPQTKKWV
MWSHWESGDGYGAARVCVATSDKIMGPYVLYKTFRPNKNESRDQTLFVDT
DGKAYHFCSTDMNTNMNIALLRDDYLEPTPTETKILKGLKYEAPAIFKVG
DMYFGLFSGCTGWEPNPGRSAYSTDILGNWTTGNNFAVDKLKQVTYNSQS
CYVFKVEGKEKAYIYMGDRWNSKDVGKSHHVWLPISMRSGYPVVKWYDQW
DLTVFNSMYRYKRAAEIIPGNIYSLLEKTSDRLVSKPANGFSIADDDDDI
NLSLEFIKTNIPNVYKIKDTKTGKFLESLFGTLRLNPEKKDDAQCWVFNL
QEDGYYQIQNLKDKKYVTVSGSNTFAGSNLYLTELSKKLMQDFAVYFDSN
KYKYKEADIFSDAYKANNLKQM
Ligand information
Ligand IDGAL
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3+,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-FPRJBGLDSA-N
SMILES
SoftwareSMILES
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O
OpenEye OEToolkits 1.7.2C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
OpenEye OEToolkits 1.7.2C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
FormulaC6 H12 O6
Namebeta-D-galactopyranose;
beta-D-galactose;
D-galactose;
galactose
ChEMBLCHEMBL300520
DrugBank
ZINCZINC000002597049
PDB chain6euf Chain E Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6euf A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		E86 R87 Y111 D143 W213
Binding residue
(residue number reindexed from 1)		E86 R87 Y111 D143 W213
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0005975 carbohydrate metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6euf, PDBe:6euf, PDBj:6euf
PDBsum6euf
PubMed30349080
UniProtQ8AB46

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