Structure of PDB 6eom Chain A Binding Site BS01

Receptor Information
>6eom Chain A (length=524) Species: 880073 (Caldithrix abyssi DSM 13497) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LKRMIAQFAPTEIKYDHSLLDERKQKVVENLYRAAKIMDEIFLDQVYSKN
FEIREQLRASSDPLDQLRLEYFTIMFGPFDRLNHDKPFIGNTPKPKGANF
YPPDMTREEFENWLKAHPEDEAAFTSEFTVIRRQDGKLVAIPYSEYYKEY
LTRAADYLKKAAEFADNPSLKKYLQLRAEAFLNNDYYESDLAWMDLNDHT
IEVVIGPYEVYEDKLFNYKAAFEAFITLRDPVESAKLKKFVGYLDEMEKN
LPIPDAYKNFNRGSESPMVVVQEVFSAGDTKAGVQTLAFNLPNDERVREA
KGSKKVMLKNIHEAKFDKLLKPIAEKVLFAEQLPLVTFEGFFNHTLMHEI
SHGLGPGKIVLNGRQTEVKKELKETYSSIEECKADVLGMYNNLFMIEKGV
YPPEFEKQIYVTFLAGIFRTIRFGINEAHGAGNAVIFNYLLEKGAYQFDP
AAHRVKVNFEKIKDGVRDLANKVLTIQAQGDYMAAKNLLETYAVESEPIM
IMRARLQELPVDIKPIFQIEKELG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6eom Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6eom The first dipeptidyl peptidase III from a thermophile: Structural basis for thermal stability and reduced activity.
Resolution2.103 Å
Binding residue
(original residue number in PDB)		H379 H383 E412
Binding residue
(residue number reindexed from 1)		H348 H352 E381
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008239 dipeptidyl-peptidase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:6eom, PDBe:6eom, PDBj:6eom
PDBsum6eom
PubMed29420664
UniProtH1XW48

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