Structure of PDB 6ejz Chain A Binding Site BS01

Receptor Information

>6ejz Chain A (length=103) Species: 585055 (Escherichia coli 55989) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLTPDEREALGT
RVRIVEELLRGEMSQRELKNELGAGIATITRGSNYLKAAPVELRQWLEEV
LLK

Ligand information

InChI=1S/C10H9NO2/c12-10(13)5-7-6-11-9-4-2-1-3-8(7)9/h1-4,6,11H,5H2,(H,12,13)

SEOVTRFCIGRIMH-UHFFFAOYSA-N

SMILES

Software	SMILES
OpenEye OEToolkits 1.7.6	c1ccc2c(c1)c(c[nH]2)CC(=O)O
ACDLabs 12.01	O=C(O)Cc2c1ccccc1nc2
CACTVS 3.370	OC(=O)Cc1c[nH]c2ccccc12

Formula

C10 H9 N O2

Name

1H-INDOL-3-YLACETIC ACID;
INDOLE ACETIC ACID

ZINC000000083860

PDB chain

6ejz Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	6ejz A biosensor for the direct visualization of auxin
Resolution	1.9 Å
Binding residue (original residue number in PDB)	R54 I57 R84 G85 Y88
Binding residue (residue number reindexed from 1)	R51 I54 R81 G82 Y85
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003700	DNA-binding transcription factor activity
GO:0043565	sequence-specific DNA binding

	Biological Process
GO:0006355	regulation of DNA-templated transcription
GO:0045892	negative regulation of DNA-templated transcription

	Cellular Component
GO:0005737	cytoplasm

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Cellular Component

External links

PDB	RCSB:6ejz, PDBe:6ejz, PDBj:6ejz
PDBsum	6ejz
PubMed
UniProt	P0A881\|TRPR_ECOLI Trp operon repressor (Gene Name=trpR)

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