Structure of PDB 6ejd Chain A Binding Site BS01

Receptor Information
>6ejd Chain A (length=693) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QPPKCDISGKEAISALSRAKSKHCRQEIGETYCRHKLGLLMPEKVTRFCP
LEGKANVEYMPANPVRIAFVLVVHGRASRQLQRMFKAIYHKDHFYYIHVD
KRSNYLHRQVLQVSRQYSNVRVTPWRMATIWGGASLLSTYLQSMRDLLEM
TDWPWDFFINLSAADYPIRTNDQLVAFLSRYRDMNFLKSHGRDNARFIRK
QGLDRLFLECDAHMWRLGDRRIPEGIAVDGGSDWFLLNRRFVEYVTFSTD
DLVTKMKQFYSYTLLPAESFFHTVLENSPHCDTMVDNNLRITNWNRKLGC
KCQYKHIVDWCGCSPNDFKPQDFHRFQQTARPTFFARKFEAVVNQEIIGQ
LDYYLYGNYPAGTPGLRSYWENVYDEPDGIHSLSDVTLTLYHSFARLGLR
RAETSLHTDGENSCRYYPMGHPASVHLYFLADRFQGFLIKHHATNLAVSK
LETLETWVMPKKVFKIDFGRLQFSEVGTDWDAKERLFRNFGGLLGPMDEP
VGMQKWGKGPNVTVTVIWVDPVNVIAATYDILIESTAEFTHYKPPLNLPL
RPGVWTVKILHHWVPVAETKFLVAPLTFSNRQPIKPEEALKLHNGPLRNA
YMEQSFQSLNPVLSLPINPAQVEQARRNAASTGTALEGWLDSLVGGMWTA
MDICATGPTACPVMQTCSQTAWSSFSPDPKSELGAVKPDGRLR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6ejd Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1.
Resolution2.684 Å
Binding residue
(original residue number in PDB)		K461 Q462 S493 E529 W555 R557 W571 C572
Binding residue
(residue number reindexed from 1)		K200 Q201 S232 E268 W294 R296 W310 C311
Enzymatic activity
Enzyme Commision number 2.4.2.26: protein xylosyltransferase.
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity
GO:0030158 protein xylosyltransferase activity
Biological Process
GO:0030166 proteoglycan biosynthetic process
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6ejd, PDBe:6ejd, PDBj:6ejd
PDBsum6ejd
PubMed29681470
UniProtQ86Y38|XYLT1_HUMAN Xylosyltransferase 1 (Gene Name=XYLT1)

[Back to BioLiP]