Structure of PDB 6ej9 Chain A Binding Site BS01

Receptor Information
>6ej9 Chain A (length=701) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DQPPKCDISGKEAISALSRAKSKHCRQEIGETYCRHKLGLLMPEKVTRFC
PLEGKANKNVWDEDSVEYMPANPVRIAFVLVVHGRASRQLQRMFKAIYHK
DHFYYIHVDKRSNYLHRQVLQVSRQYSNVRVTPWRMATIWGGASLLSTYL
QSMRDLLEMTDWPWDFFINLSAADYPIRTNDQLVAFLSRYRDMNFLKSHG
RDNARFIRKQGLDRLFLECDAHMWRLGDRRIPEGIAVDGGSDWFLLNRRF
VEYVTFSTDDLVTKMKQFYSYTLLPAESFFHTVLENSPHCDTMVDNNLRI
TNWNRKLGCKCQYKHIVDWCGCSPNDFKPQDFHRFQQTARPTFFARKFEA
VVNQEIIGQLDYYLYGNYPAGTPGLRSYWENVYDEPDGIHSLSDVTLTLY
HSFARLGLRRAETSLHTDGENSCRYYPMGHPASVHLYFLADRFQGFLIKH
HATNLAVSKLETLETWVMPKKVFKIFGRLQFSEVGTDWDAKERLFRNFGG
LLGPMDEPVGMQKWGKGPNVTVTVIWVDPVNVIAATYDILIESTAEFTHY
KPPLNLPLRPGVWTVKILHHWVPVAETKFLVAPLTFSNRQPIKPEEALKL
HNGPLRNAYMEQSFQSLNPVLSLPINPAQVEQARRNAASTGTALEGWLDS
LVGGMWTAMDICATGPTACPVMQTCSQTAWSSFSPDPKSELGAVKPDGRL
R
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ej9 Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1.
Resolution2.02 Å
Binding residue
(original residue number in PDB)		H451 K461 Q462 R466 S493 E529 W555 R557 W571 C572 G573 C574
Binding residue
(residue number reindexed from 1)		H199 K209 Q210 R214 S241 E277 W303 R305 W319 C320 G321 C322
Enzymatic activity
Enzyme Commision number 2.4.2.26: protein xylosyltransferase.
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity
GO:0030158 protein xylosyltransferase activity
Biological Process
GO:0030166 proteoglycan biosynthetic process
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ej9, PDBe:6ej9, PDBj:6ej9
PDBsum6ej9
PubMed29681470
UniProtQ86Y38|XYLT1_HUMAN Xylosyltransferase 1 (Gene Name=XYLT1)

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