Structure of PDB 6e8c Chain A Binding Site BS01
Receptor Information
>6e8c Chain A (length=135) Species:
9606
(Homo sapiens) [
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RGRGRRRRLVWTPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQI
WFQNERSRQLRQHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEK
DRFPGIAAREELARETGLPESRIQIWFQNRRARHP
Ligand information
>6e8c Chain B (length=17) [
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gcgtaatctaatcaaca
Receptor-Ligand Complex Structure
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PDB
6e8c
Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA.
Resolution
2.12 Å
Binding residue
(original residue number in PDB)
R16 R20 R21 R23 L24 W26 R62 I65 N69 R73 R98 F118 R124 Q139 Q143 R146
Binding residue
(residue number reindexed from 1)
R1 R5 R6 R8 L9 W11 R47 I50 N54 R58 R83 F103 R109 Q124 Q128 R131
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
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Molecular Function
External links
PDB
RCSB:6e8c
,
PDBe:6e8c
,
PDBj:6e8c
PDBsum
6e8c
PubMed
30540931
UniProt
Q9UBX2
|DUX4_HUMAN Double homeobox protein 4 (Gene Name=DUX4)
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