Structure of PDB 6e25 Chain A Binding Site BS01

Receptor Information
>6e25 Chain A (length=97) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSDYENDDECWSVLEGFRVTLTSVIDPSRITPYLRQCKVLNPDDEEQVLS
DPNLVIRKRKVGVLLDILQRTGHKGYVAFLESLELYYPQLYKKVTGK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6e25 Chain A Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6e25 Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9.
ResolutionN/A
Binding residue
(original residue number in PDB)		D7 C10 H73
Binding residue
(residue number reindexed from 1)		D7 C10 H73
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

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Biological Process
External links
PDB RCSB:6e25, PDBe:6e25, PDBj:6e25
PDBsum6e25
PubMed30206119
UniProtQ9H257|CARD9_HUMAN Caspase recruitment domain-containing protein 9 (Gene Name=CARD9)

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