Structure of PDB 6du2 Chain A Binding Site BS01

Receptor Information
>6du2 Chain A (length=180) Species: 9365 (Erinaceus europaeus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QYLLPEAKAQDSDKICVVINLDETLVHSSFKPVNNADFIIPVEIDGVVHQ
VYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARL
FRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWF
DNMSDTELHDLLPFFEQLSRVDDVYSVLRQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6du2 Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
Resolution2.5 Å
Binding residue
(original residue number in PDB)		N96 D98 T152 A153 S154 R178 F183 G186 Y188
Binding residue
(residue number reindexed from 1)		N20 D22 T76 A77 S78 R102 F107 G110 Y112
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Gene Ontology
Molecular Function
GO:0016791 phosphatase activity

View graph for
Molecular Function
External links
PDB RCSB:6du2, PDBe:6du2, PDBj:6du2
PDBsum6du2
PubMed30217818
UniProtA0A1S2ZIM2

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