Structure of PDB 6du0 Chain A Binding Site BS01

Receptor Information
>6du0 Chain A (length=180) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DEINAQSVWSEEISSNYPLCIKNLMEGLKKNHHLRYYGRQQLSLFLKGIG
LSADEALKFWSEAFTRNGNMTMEKFNKELRYSFRHNYGLERINYKPWDCH
TILSKPRPGRGDYHGCPFRDWSHERLSAELRSMKLTQAQIISVLDSCQKG
EYTIACTKVFEMTHIAHPNLYFERSRQLQK
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain6du0 Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6du0 Yeast require redox switching in DNA primase.
Resolution1.82 Å
Binding residue
(original residue number in PDB)		P334 C336 C417 C434 F436 C474 P500
Binding residue
(residue number reindexed from 1)		P18 C20 C99 C116 F118 C156 P168
Annotation score4
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Biological Process
GO:0006269 DNA replication, synthesis of primer

View graph for
Biological Process
External links
PDB RCSB:6du0, PDBe:6du0, PDBj:6du0
PDBsum6du0
PubMed30541886
UniProtP20457|PRI2_YEAST DNA primase large subunit (Gene Name=PRI2)

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