Structure of PDB 6dtv Chain A Binding Site BS01

Receptor Information
>6dtv Chain A (length=184) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DDEINAQSVWSEEISSNYPLCIKNLMEGLKKNHHLRYYGRQQLSLFLKGI
GLSADEALKFWSEAFTRNGNMTMEKFNKEFRYSFRHNYGLEGNRINYKPW
DCHTILSKPRPGRGDYHGCPFRDWSHERLSAELRSMKLTQAQIISVLDSC
QKGEYTIACTKVFEMTHNIAHPNLYFERSRQLQK
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain6dtv Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6dtv Yeast require redox switching in DNA primase.
Resolution1.12 Å
Binding residue
(original residue number in PDB)		P334 C336 C417 I420 C434 F436 T471 C474 P500
Binding residue
(residue number reindexed from 1)		P19 C21 C102 I105 C119 F121 T156 C159 P172
Annotation score4
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Biological Process
GO:0006269 DNA replication, synthesis of primer

View graph for
Biological Process
External links
PDB RCSB:6dtv, PDBe:6dtv, PDBj:6dtv
PDBsum6dtv
PubMed30541886
UniProtP20457|PRI2_YEAST DNA primase large subunit (Gene Name=PRI2)

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