Structure of PDB 6dqq Chain A Binding Site BS01

Receptor Information

>6dqq Chain A (length=521) Species: 281310 (Haemophilus influenzae 86-028NP)

VIVPEGTQLDEKQHIVINNGAEPQSFDPHKTEGVPESNVAYQLLEGLVTS
DSEGKLQPGAAESWENTPDFKTWTFHLRKDAKWSNGDPVTAHDFVFAWRR
LVDPATAAPYASYLSYLQVENAQDIIDGKKKPAELGVEAKDDYTFVVHAT
NPVPYAVSLTTHQSLLPLPQKVVEKLGDAWVKKENYVGNGAYKLANHIIN
EKIEFERNPLYWNDKETVINSATFLAIENPSTDVARYRAGDLDMTSYGLP
PEQFAKLKKELLGEVYVTRTLGTYSYELNNKKAPFDNVNIRKALNLSLDR
NVITDKVLGQGQTPTYVFTPTYIEEGHLIQQPAYSKEPMAQRNEEAIKLL
EEAGYSKANPLKFSILYNTNENHKKVAIAAASMWKANTKGLIDVKLENQE
WKTYIDSRRAGRYDVARAGWHADYNQATTFGNYFLSNSSNNTAKYANPEY
DKAMAESYAATDAEGRAKAYAKAEEILGKDYGIVPIFNYVNPRLVKPYVK
GYSGKDPQDHIYLRNLYIIKH

Ligand information

>6dqq Chain B (length=4) Species: 32630 (synthetic construct)

AAAA

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6dqq Oligopeptide-binding protein from nontypeableHaemophilus influenzaehas ligand-specific sites to accommodate peptides and heme in the binding pocket.
• Resolution: 1.85 Å
• Binding residue (original residue number in PDB): E52 G53 V54 Y130 Y267 N388 H393 W421 R437 G439 W440 H441 D443
• Binding residue (residue number reindexed from 1): E32 G33 V34 Y110 Y247 N368 H373 W401 R417 G419 W420 H421 D423

Gene Ontology

Molecular Function

• GO:1904680 peptide transmembrane transporter activity

Biological Process

• GO:0015833 peptide transport
• GO:0055085 transmembrane transport

Cellular Component

• GO:0030288 outer membrane-bounded periplasmic space
• GO:0043190 ATP-binding cassette (ABC) transporter complex

External links

• PDB: RCSB:6dqq, PDBe:6dqq, PDBj:6dqq
• PDBsum: 6dqq
• PubMed: 30455346
• UniProt: Q4QLH0