Structure of PDB 6dos Chain A Binding Site BS01

Receptor Information
>6dos Chain A (length=135) Species: 86665 (Halalkalibacterium halodurans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEIIWESLSVDVGSQGNPGIVEYKGVDTKTGEVLFEREPIPIGTNNMGEF
LAIVHGLRYLKERNSRKPIYSDSQTAIKWVKDKKAKSTLVRNEETALIWK
LVDEAEEWLNTHTYETPILKWQTDKWGEIKADYGR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6dos Cation trafficking propels RNA hydrolysis.
Resolution1.318 Å
Binding residue
(original residue number in PDB)		D132 Q134 K180 T183
Binding residue
(residue number reindexed from 1)		D72 Q74 K120 T123
Enzymatic activity
Enzyme Commision number 3.1.26.4: ribonuclease H.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004523 RNA-DNA hybrid ribonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:6dos, PDBe:6dos, PDBj:6dos
PDBsum6dos
PubMed30076410
UniProtQ9KEI9|RNH1_HALH5 Ribonuclease H (Gene Name=rnhA)

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