Structure of PDB 6do4 Chain A Binding Site BS01

Receptor Information
>6do4 Chain A (length=319) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ACPAERSGHVAVSDGRHMFVWGGYKSFYLPREELWIYNMETGRWKKINTE
GDVPPSMSGSCAVCVDRVLYLFGGHHSRGNTNKFYMLDSRSRVLQWERID
CQGIPPSSKDKLGVWVYKNKLIFFGGYGYLPKVLGTFEFDETSFWSHPRG
WNDHVHILDTETFTWSQPITTGKAPSPRAAHACATVGNRGFVFGGRYRDA
RMNDLHYLNLDTWEWNELIPQGICPVGRSWHSLTPVSSDHLFLFGGFTTD
KQPLSDAWTYCISKNEWIQFNHPYTEKPRLWHTACASDEGEVIVFGGCAN
NLLVHHRAAHSNEILIFSV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6do4 Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase.
Resolution2.2 Å
Binding residue
(original residue number in PDB)
K147 Y163 R189 W191 R236 R241 S269 W270 W321
Binding residue
(residue number reindexed from 1)
K111 Y127 R149 W151 R196 R201 S229 W230 W281
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6do4, PDBe:6do4, PDBj:6do4
PDBsum6do4
PubMed30526872
UniProtQ9Y2U9|KLDC2_HUMAN Kelch domain-containing protein 2 (Gene Name=KLHDC2)

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