Structure of PDB 6do3 Chain A Binding Site BS01
Receptor Information
>6do3 Chain A (length=317) Species:
9606
(Homo sapiens) [
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ACPAERSGHVAVSDGRHMFVWGGYKSFYLPREELWIYNMETGRWKKINTE
GDVPPSMSGSCAVCVDRVLYLFGGHHSRGNTNKFYMLDSLQWERIDCQGI
PPSSKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWNHPRGWN
DHVHILDTETFTWSQPITTGKAPSPRAAHACATVGNRGFVFGGRYRDARM
NDLHYLNLDTWEWNELIPQGICPVGRSWHSLTPVSSDHLFLFGGFTTDKQ
PLSDAWTYCISKNEWIQFNHPYTEKPRLWHTACASDEGEVIVFGGCANNL
LVHHRAAHSNEILIFSV
Ligand information
>6do3 Chain C (length=7) Species:
9606
(Homo sapiens) [
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PPPMAGG
Receptor-Ligand Complex Structure
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PDB
6do3
Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase.
Resolution
2.165 Å
Binding residue
(original residue number in PDB)
Y50 H109 K147 Y163 R189 W191 R236 R241 S269 W270 L342
Binding residue
(residue number reindexed from 1)
Y24 H75 K107 Y123 R147 W149 R194 R199 S227 W228 L300
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6do3
,
PDBe:6do3
,
PDBj:6do3
PDBsum
6do3
PubMed
30526872
UniProt
Q9Y2U9
|KLDC2_HUMAN Kelch domain-containing protein 2 (Gene Name=KLHDC2)
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