Structure of PDB 6dew Chain A Binding Site BS01

Receptor Information
>6dew Chain A (length=195) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YESEEQLQHRILTAALEFVPAHGWTAEAIAEGAQSLGLSSAAASMFGKDG
SELILHFVTQCNTRLTRVLEEEQKLVQLGQAEKRKTDQFLRDAVETRLRM
LIPYIEHWPRALSILMLPHNIPSSLSLLTSMVDDMWHYAGDQSTDFNWYT
RRAMLAAIYNTTELVMMQDSSPDFEDTWRFLENRVNDAMNMGHTA
Ligand information
Ligand IDFOF
InChIInChI=1S/C15H26O/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-16/h7,9,11,16H,5-6,8,10,12H2,1-4H3/b14-9+,15-11+
InChIKeyCRDAMVZIKSXKFV-YFVJMOTDSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7CC(=CCCC(=CCCC(=CCO)C)C)C
CACTVS 3.385CC(C)=CCCC(C)=CCCC(C)=CCO
CACTVS 3.385CC(C)=CCC\C(C)=C\CC/C(C)=C/CO
ACDLabs 12.01C\C(=C\CC\C(=C\CCC(C)=[C@H]CO)C)C
OpenEye OEToolkits 2.0.7CC(=CCC/C(=C/CC/C(=C/CO)/C)/C)C
FormulaC15 H26 O
Name(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol;
trans,trans-Farnesol
ChEMBLCHEMBL25308
DrugBank
ZINCZINC000001532860
PDB chain6dew Chain A Residue 304 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6dew An Isoprene Lipid-Binding Protein Promotes Eukaryotic Coenzyme Q Biosynthesis.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		V150 N154 L207 M208 L217 M223
Binding residue
(residue number reindexed from 1)		V58 N62 L115 M116 L125 M131
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006744 ubiquinone biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6dew, PDBe:6dew, PDBj:6dew
PDBsum6dew
PubMed30661980
UniProtO75208|COQ9_HUMAN Ubiquinone biosynthesis protein COQ9, mitochondrial (Gene Name=COQ9)

[Back to BioLiP]