Structure of PDB 6dbo Chain A Binding Site BS01

Receptor Information
>6dbo Chain A (length=542) Species: 7955,83333 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKEL
LPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYD
VALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSVPE
KAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDH
ETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREM
EGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPF
SESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEV
YQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEA
VCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQ
FADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGN
KLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6dbo DNA melting initiates the RAG catalytic pathway.
Resolution4.4 Å
Binding residue
(original residue number in PDB)		D620 G623 E731 S743 R845 M869 R870 T955 N956 K988 R992
Binding residue
(residue number reindexed from 1)		D141 G144 E244 S256 R358 M382 R383 T468 N469 K501 R505
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0005515 protein binding
GO:0015144 carbohydrate transmembrane transporter activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
GO:1901982 maltose binding
Biological Process
GO:0006974 DNA damage response
GO:0008643 carbohydrate transport
GO:0015768 maltose transport
GO:0033151 V(D)J recombination
GO:0034219 carbohydrate transmembrane transport
GO:0034289 detection of maltose stimulus
GO:0042956 maltodextrin transmembrane transport
GO:0055085 transmembrane transport
GO:0060326 cell chemotaxis
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
GO:1990060 maltose transport complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6dbo, PDBe:6dbo, PDBj:6dbo
PDBsum6dbo
PubMed30061602
UniProtO13033|RAG1_DANRE V(D)J recombination-activating protein 1 (Gene Name=rag1);
P0AEX9|MALE_ECOLI Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE)

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