Structure of PDB 6dbj Chain A Binding Site BS01

Receptor Information
>6dbj Chain A (length=552) Species: 7955,83333 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FGLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKE
LLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRY
DVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEK
HGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLC
LMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTG
YDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLER
YEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYK
IFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARR
LMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQL
CQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAW
ASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAH
KN
Ligand information
Receptor-Ligand Complex Structure
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PDB6dbj DNA melting initiates the RAG catalytic pathway.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		S496 C497 S498 R523 M996 N997 A998 R999 K1011
Binding residue
(residue number reindexed from 1)		S18 C19 S20 R45 M518 N519 A520 R521 K533
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0005515 protein binding
GO:0015144 carbohydrate transmembrane transporter activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
GO:1901982 maltose binding
Biological Process
GO:0006974 DNA damage response
GO:0008643 carbohydrate transport
GO:0015768 maltose transport
GO:0033151 V(D)J recombination
GO:0034219 carbohydrate transmembrane transport
GO:0034289 detection of maltose stimulus
GO:0042956 maltodextrin transmembrane transport
GO:0055085 transmembrane transport
GO:0060326 cell chemotaxis
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
GO:1990060 maltose transport complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6dbj, PDBe:6dbj, PDBj:6dbj
PDBsum6dbj
PubMed30061602
UniProtO13033|RAG1_DANRE V(D)J recombination-activating protein 1 (Gene Name=rag1);
P0AEX9|MALE_ECOLI Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE)

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