Structure of PDB 6d78 Chain A Binding Site BS01

Receptor Information
>6d78 Chain A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6d78 Improving T Cell Receptor On-Target Specificity via Structure-Guided Design.
Resolution2.347 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 H70 D77 Y99 Y116 T143 K146 W147 V152 Q155 L156 Y159
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 H70 D77 Y99 Y116 T143 K146 W147 V152 Q155 L156 Y159
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6d78, PDBe:6d78, PDBj:6d78
PDBsum6d78
PubMed30617019
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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