Structure of PDB 6cv1 Chain A Binding Site BS01

Receptor Information
>6cv1 Chain A (length=290) Species: 42789 (enterovirus D68) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IESIIKTATDTVKSEINAELGVVPSLNAVETGATSNTEPEEAIQTRTVIN
QHGVSETLVENFLSRAALVSKRSFEYKDHTSSAAQTDKNFFKWTINTRSF
VQLRRKLELFTYLRFDAEITILTTVAVNTYMGLPNLTLQAMFVPTGALTP
EKQDSFHWQSGSNASVFFKISDPPARMTIPFMCINSAYSVFYDGFAGFEK
SGLYGINPADTIGNLCVRIVNEHQPVGFTVTVRVYMKPKHIKAWAPRPPR
TLPYMSIANANYKGKKRAPNALNAIIGNRDSVKTMPHNIV
Ligand information
>6cv1 Chain D (length=29) Species: 42789 (enterovirus D68) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
NFYKDSYAASASKQDFSQDPSKFTEPVVE
Receptor-Ligand Complex Structure
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PDB6cv1 Bypassing pan-enterovirus host factor PLA2G16.
Resolution2.76 Å
Binding residue
(original residue number in PDB)		E2 S3 I4 I5 A33 T34 S55 L58 E60 D116 T183 P185 K244 H245 P251
Binding residue
(residue number reindexed from 1)		E2 S3 I4 I5 A33 T34 S55 L58 E60 D116 T178 P180 K239 H240 P246
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
External links