Structure of PDB 6cs3 Chain A Binding Site BS01

Receptor Information
>6cs3 Chain A (length=267) Species: 42789 (enterovirus D68) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IESIIKTATDTVKSELGVVPSLNAVETGATSNTEPEEAIQTRTVINQHGV
SETLVENFLSRAALVSKRSFEYKDKNFFKWTINTRSFVQLRRKLELFTYL
RFDAEITILTTVAVGLPDLTLQAMFVPTGALTPEKQDSFHWQSGSNASVF
FKISDPPARITIPFMCINSAYSVFYDGFAGFEKNGLYGINPADTIGNLCV
RIVNEHQPVGFTVTVRVYMKPKHIKAWAPRPPRTLPYMSIANANYKGKER
APNALSAIIGNRDSVKT
Ligand information
>6cs3 Chain D (length=28) Species: 42789 (enterovirus D68) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
NFYKDSYAASASKQDFSQDPSKFTEPVV
Receptor-Ligand Complex Structure
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PDB6cs3 Molecular basis for the acid-initiated uncoating of human enterovirus D68.
Resolution3.31 Å
Binding residue
(original residue number in PDB)		I1 E2 S3 I5 K6 A33 T34 S55 L58 E60 N61 T183 P185 K244 H245
Binding residue
(residue number reindexed from 1)		I1 E2 S3 I5 K6 A29 T30 S51 L54 E56 N57 T161 P163 K222 H223
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
External links