Structure of PDB 6crp Chain A Binding Site BS01
Receptor Information
>6crp Chain A (length=242) Species:
42789
(enterovirus D68) [
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QHGVSETLVENFLSRAALVSKRSFEYKDHTSSTARADKNFFKWTINTRSF
VQLRRKLELFTYLRFDAEITILTTVAVNNTYVGLPDLTLQAMFVPTGALT
PEKQDSFHWQSGSNASVFFKISDPPARITIPFMCINSAYSVFYDGFAGFE
KNGLYGINPADTIGNLCVRIVNEHQPVGFTVTVRVYMKPKHIKAWAPRPP
RTLPYMSIANANYKGKERAPNALSAIIGNRDSVKTMPHNIVN
Ligand information
>6crp Chain D (length=18) Species:
42789
(enterovirus D68) [
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NQINFYKDSYAASASKQD
Receptor-Ligand Complex Structure
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PDB
6crp
Molecular basis for the acid-initiated uncoating of human enterovirus D68.
Resolution
3.24 Å
Binding residue
(original residue number in PDB)
L58 E60 D116 T183 P185 K244 H245
Binding residue
(residue number reindexed from 1)
L8 E10 D66 T129 P131 K190 H191
Enzymatic activity
Enzyme Commision number
2.7.7.48
: RNA-directed RNA polymerase.
3.4.22.28
: picornain 3C.
3.4.22.29
: picornain 2A.
3.6.1.15
: nucleoside-triphosphate phosphatase.
External links
PDB
RCSB:6crp
,
PDBe:6crp
,
PDBj:6crp
PDBsum
6crp
PubMed
30530701
UniProt
A0A097BW12
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