Structure of PDB 6cim Chain A Binding Site BS01

Receptor Information
>6cim Chain A (length=611) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNE
HRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGR
QIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASS
VDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVV
VKESCDGMGDVSEKHGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKP
NSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPR
TFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSI
TRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHC
DIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPI
MRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSS
CPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEI
IERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTS
KYLQKFMNAHN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6cim Cracking the DNA Code for V(D)J Recombination.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		R848 M849 N965 R969
Binding residue
(residue number reindexed from 1)		R452 M453 N569 R573
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6cim, PDBe:6cim, PDBj:6cim
PDBsum6cim
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

[Back to BioLiP]