Structure of PDB 6cgv Chain A Binding Site BS01

Receptor Information
>6cgv Chain A (length=917) Species: 28285 (Human adenovirus 5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQWSYMHISGQDASEYLSPGLVQFARATETYFSLNNKFRNPTVAPTHDVT
TDRSQRLTLRFIPVDREDTAYSYKARFTLAVGDNRVLDMASTYFDIRGVL
DRGPTFKPYSGTAYNALAPKGAPNPCEWDETHVFGQAPYSGINITKEGIQ
IGVEGQTPKYADKTFQPEPQIGESQWYETEINHAAGRVLKKTTPMKPCYG
SYAKPTNENGGQGILVKQQNGKLESQVEMQFFSTTEATAGNGDNLTPKVV
LYSEDVDIETPDTHISYMPTIKEGNSRELMGQQSMPNRPNYIAFRDNFIG
LMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSIGDRTRYFS
MWNQAVDSYDPDVRIIENHGTEDELPNYCFPLGGVINTETLTKVKPKTGQ
ENGWEKDATEFSDKNEIRVGNNFAMEINLNANLWRNFLYSNIALYLPDKL
KYSPSNVKISDNPNTYDYMNKRVVAPGLVDCYINLGARWSLDYMDNVNPF
NHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNF
RKDVNMVLQSSLGNDLRVDGASIKFDSICLYATFFPMAHNTASTLEAMLR
NDTNDQSFNDYLSAANMLYPIPANATNVPISIPSRNWAAFRGWAFTRLKT
KETPSLGSGYDPYYTYSGSIPYLDGTFYLNHTFKKVAITFDSSVSWPGND
RLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPE
SYKDRMYSFFRNFQPMSRQVVDDTKYKDYQQVGILHQHNNSGFVGYLAPT
MREGQAYPANFPYPLIGKTAVDSITQKKFLCDRTLWRIPFSSNFMSMGAL
TDLGQNLLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDVVRVHRPHRGV
IETVYLRTPFSAGNATT
Ligand information
>6cgv Chain W (length=24) Species: 28285 (Human adenovirus 5) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
FASLAPRHGSRPFMGNWQDIGTSN
Receptor-Ligand Complex Structure
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PDB6cgv Revised Crystal Structure of Human Adenovirus Reveals the Limits on Protein IX Quasi-Equivalence and on Analyzing Large Macromolecular Complexes.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		G17 Q18 D19 P48 P52 D55 V56 D645 Y646 N773
Binding residue
(residue number reindexed from 1)		G10 Q11 D12 P41 P45 D48 V49 D610 Y611 N738
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0046718 symbiont entry into host cell
GO:0075521 microtubule-dependent intracellular transport of viral material towards nucleus
Cellular Component
GO:0019028 viral capsid
GO:0039623 T=25 icosahedral viral capsid
GO:0042025 host cell nucleus
GO:0043657 host cell

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6cgv, PDBe:6cgv, PDBj:6cgv
PDBsum6cgv
PubMed30121295
UniProtP04133|CAPSH_ADE05 Hexon protein (Gene Name=L3)

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