Structure of PDB 6cgb Chain A Binding Site BS01

Receptor Information

>6cgb Chain A (length=204) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVI
DDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDIN
DNEPIFTKDVYTATVPEMADVGTFVVQVTATDADDPTYGNSAKVVYSILQ
GQPYFSVESETGIIKTALLNMNREQYQVVIQAKDMGGQMGGLSGTTTVNI
TLTD

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

6cgb Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6cgb Homophilic and Heterophilic Interactions of Type II Cadherins Identify Specificity Groups Underlying Cell-Adhesive Behavior.
Resolution	2.994 Å
Binding residue (original residue number in PDB)	E11 E66 D98 I99 D101 D134
Binding residue (residue number reindexed from 1)	E11 E66 D98 I99 D101 D134
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding

	Biological Process
GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609	cell-cell adhesion

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

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Cellular Component

External links

PDB	RCSB:6cgb, PDBe:6cgb, PDBj:6cgb
PDBsum	6cgb
PubMed	29742438
UniProt	P55288\|CAD11_MOUSE Cadherin-11 (Gene Name=Cdh11); P97326\|CADH6_MOUSE Cadherin-6 (Gene Name=Cdh6)

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