Structure of PDB 6cfi Chain A Binding Site BS01

Receptor Information
>6cfi Chain A (length=496) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RNVCSNEERKRRKYFHMLYLVCLMVHGFIRNEWINSKRLSRKLSNLVPEK
VFELLHPQKDEELPLRSTRKLLDGLKKCMELWQKHWKITKKYDNEGLYMR
TWKEIEMSANNKRKFKTLKRSDFLRAVSKGHGDPDISVQGFVAMLRACNV
NARLIMSCQPPDFTNMKIDTSLNGNNAYKDMVKYPIFWCEVWDKFSKKWI
TVDPVNLKTIEQVRLHSKLAPKGVACCERNMLRYVIAYDRKYGCRDVTRR
YAQWMNSKVRKRRITKDDFGEKWFRKVITALHHRKRTKIDDYEDQYFFRR
DESEGIPDSVQDLKNHPYYVLEQDIKQTQIVKPGCKECGYLKVHGKVGKV
LKVYAKRDIADLKSARQWYMNGRILKTGSRCKKVIKRTVEEDERLYSFED
TELYIPPLASASGEITKNTFGNIEVFAPTMIPGNCCLVENPVAIKAARFL
GVEFAPAVTSFKFERGSTVKPVLSGIVVAKWLREAIETAIDGIEFI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6cfi Structure and mechanism of pyrimidine-pyrimidone (6-4) photoproduct recognition by the Rad4/XPC nucleotide excision repair complex.
Resolution3.36242 Å
Binding residue
(original residue number in PDB)		R129 N134 S437 V438 Q439 H472 Q495 M498 F556 E560 F597 F599 T604 P607
Binding residue
(residue number reindexed from 1)		R1 N6 S309 V310 Q311 H344 Q367 M370 F420 E424 F461 F463 T468 P471
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
Biological Process
GO:0006289 nucleotide-excision repair
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6cfi, PDBe:6cfi, PDBj:6cfi
PDBsum6cfi
PubMed31106376
UniProtP14736|RAD4_YEAST DNA repair protein RAD4 (Gene Name=RAD4)

[Back to BioLiP]