Structure of PDB 6cc8 Chain A Binding Site BS01
Receptor Information
>6cc8 Chain A (length=71) Species:
9606
(Homo sapiens) [
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MERKRWECPALPQGWEREEVPRRSGLSAGHRDVFYYSPSGKKFRSKPQLA
RYLGGSMDLSTFDFRTGKMLM
Ligand information
>6cc8 Chain C (length=12) [
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gccaacgttggc
Receptor-Ligand Complex Structure
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PDB
6cc8
Structural analyses reveal that MBD3 is a methylated CG binder.
Resolution
1.95 Å
Binding residue
(original residue number in PDB)
R22 R23 S24 L26 S27 K42
Binding residue
(residue number reindexed from 1)
R22 R23 S24 L26 S27 K42
Binding affinity
PDBbind-CN
: Kd=5.4uM
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
View graph for
Molecular Function
External links
PDB
RCSB:6cc8
,
PDBe:6cc8
,
PDBj:6cc8
PDBsum
6cc8
PubMed
30980593
UniProt
O95983
|MBD3_HUMAN Methyl-CpG-binding domain protein 3 (Gene Name=MBD3)
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