Structure of PDB 6c98 Chain A Binding Site BS01

Receptor Information

>6c98 Chain A (length=262) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

HLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVW
ENQVSWYWEKETTDLRIKEKLFLEAFKALGGPYTLQGLLGCELGPDNTSV
PTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFL
LFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYP
PELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQ
HAGLAQPLRVEL

Ligand information

Ligand ID

CYS

InChI

InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1

InChIKey

XUJNEKJLAYXESH-REOHCLBHSA-N

SMILES

Software	SMILES
CACTVS 3.341	N[CH](CS)C(O)=O
OpenEye OEToolkits 1.5.0	C([C@@H](C(=O)O)N)S
CACTVS 3.341	N[C@@H](CS)C(O)=O
ACDLabs 10.04	O=C(O)C(N)CS
OpenEye OEToolkits 1.5.0	C(C(C(=O)O)N)S

Formula

C3 H7 N O2 S

Name

CYSTEINE

PDB chain

6c98 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6c98 Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.
Resolution	1.85 Å
Binding residue (original residue number in PDB)	P47 C48
Binding residue (residue number reindexed from 1)	P44 C45
Annotation score	4

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:6c98, PDBe:6c98, PDBj:6c98
PDBsum	6c98
PubMed	29782488
UniProt	P55899\|FCGRN_HUMAN IgG receptor FcRn large subunit p51 (Gene Name=FCGRT)

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