Structure of PDB 6c46 Chain A Binding Site BS01

Receptor Information

>6c46 Chain A (length=183) Species: 1338011 (Elizabethkingia anophelis NUHP1)

HHMKLVKTPLKDCYIIEPTVFEDERGYFYEKYNEKKFEELTGLNGHFVQD
NISKSSYGVLRGLHLQKGKHAQAKLVSCLEGRVWDVAVDLRENSETFGKC
YGMELSAENKLQFYVPRGFAHGFVVLSETAVFSYKCDNFYNKESEGSVKF
NDSDLSIDWKIPEADMILSEKDQNAPAFKDKNY

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 6c46 Chain A Residue 200

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6c46 Crystal structure of dTDP-4-dehydrorhamnose 3,5-epimerase from Elizabethkingia anophelis NUHP1
• Resolution: 1.95 Å
• Binding residue (original residue number in PDB): E32 E36
• Binding residue (residue number reindexed from 1): E34 E38
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): H62 K72 Y132 D170
• Catalytic site (residue number reindexed from 1): H64 K74 Y134 D172
• Enzyme Commision number: 5.1.3.13: dTDP-4-dehydrorhamnose 3,5-epimerase.

Gene Ontology

Molecular Function

• GO:0008830 dTDP-4-dehydrorhamnose 3,5-epimerase activity
• GO:0016853 isomerase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0019305 dTDP-rhamnose biosynthetic process
• GO:0045226 extracellular polysaccharide biosynthetic process

Cellular Component

• GO:0005829 cytosol

External links

• PDB: RCSB:6c46, PDBe:6c46, PDBj:6c46
• PDBsum: 6c46
• UniProt: A0A077ENB9