Structure of PDB 6c1k Chain A Binding Site BS01

Receptor Information
>6c1k Chain A (length=221) Species: 367737 (Aliarcobacter butzleri RM4018) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MYLRITNIVESSFFTKFIIYLIVLNGITMGLETSKTFMQSFGVYTTLFNQ
IVITIFTIEIILRIYVHRISFFKDPWSLFDFFVVAISLVPTSSGFEILRV
LGVLRLFRLVTAVPQMRKIVSALISVIPGMLSVIALMTLFFYIFAIMATQ
LFGERFPEWFGTLGESFYTLFQVMTLESWSMGIVRPLMEVYPYAWVFFIP
FIFVVTFVMINLVVAICVDAM
Ligand information
Ligand IDNA
InChIInChI=1S/Na/q+1
InChIKeyFKNQFGJONOIPTF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Na+]
FormulaNa
NameSODIUM ION
ChEMBL
DrugBankDB14516
ZINC
PDB chain6c1k Chain A Residue 1311 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6c1k Structural basis for gating pore current in periodic paralysis.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		W1159 G1182
Binding residue
(residue number reindexed from 1)		W159 G182
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0005248 voltage-gated sodium channel activity
GO:0005261 monoatomic cation channel activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006811 monoatomic ion transport
GO:0035725 sodium ion transmembrane transport
GO:0055085 transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0001518 voltage-gated sodium channel complex
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6c1k, PDBe:6c1k, PDBj:6c1k
PDBsum6c1k
PubMed29769724
UniProtA8EVM5

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