Structure of PDB 6bwn Chain A Binding Site BS01

Receptor Information
>6bwn Chain A (length=206) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NQSPPRFPQLMYSLEVSEAMRIGAILLNLQATDREGDPITYAIENGDPQR
VFNLSETTGILSLGKALDRESTDRYILIVTASDGRPDGTSTATVNIVVTD
VNDNAPVFDPYLPRNLSVVEEEANAFVGQVRATDPDAGINGQVHYSLGNF
NNLFRITSNGSIYTAVKLNREARDHYELVVVATDGAVHPRHSTLTLYIKV
LDIDLE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6bwn Chain A Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6bwn Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception.
Resolution2.94 Å
Binding residue
(original residue number in PDB)		E606 E658 D688 V689 D691 D724
Binding residue
(residue number reindexed from 1)		E18 E70 D100 V101 D103 D136
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6bwn, PDBe:6bwn, PDBj:6bwn
PDBsum6bwn
PubMed32963095
UniProtQ99PJ1|PCD15_MOUSE Protocadherin-15 (Gene Name=Pcdh15)

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