Structure of PDB 6bpi Chain A Binding Site BS01
Receptor Information
>6bpi Chain A (length=206) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
ENLYFQGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGK
SLLSGNHIAYDYHPPADKLYVGSRVVAKYKVWLYAGIVAETPNVKNKLRF
LIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNR
PMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGST
RLEPMF
Ligand information
>6bpi Chain B (length=4) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
KSTG
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
6bpi
Crystal structure of SETDB1 Tudor domain with aryl triazole fragment peptide conjugates
Resolution
1.64 Å
Binding residue
(original residue number in PDB)
G300 A302 C329 F332 W358 F379 D382 R384 E386 I388 Y389 S392 R394
Binding residue
(residue number reindexed from 1)
G107 A109 C136 F139 W165 F186 D189 R191 E193 I195 Y196 S199 R201
Enzymatic activity
Enzyme Commision number
2.1.1.366
: [histone H3]-N(6),N(6)-dimethyl-lysine(9) N-methyltransferase.
External links
PDB
RCSB:6bpi
,
PDBe:6bpi
,
PDBj:6bpi
PDBsum
6bpi
PubMed
UniProt
Q15047
|SETB1_HUMAN Histone-lysine N-methyltransferase SETDB1 (Gene Name=SETDB1)
[
Back to BioLiP
]
