Structure of PDB 6bms Chain A Binding Site BS01

Receptor Information
>6bms Chain A (length=281) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RCCQRIFSWIPVIIISSVVLWSYYAYVFELCFVTNNLERVTYLLIFHVCF
IMFCWTYWKAIFTPPSTPTKKFHLSYTDKERYRPEVQKQILVDIAKKLPI
FTRAQSGAIRFCDRCQVIKPDRCHHCSVCETCVLKMDHHSPWVNNCVGFS
NYKFFLLFLSYSMIYCVFIASTVFQYFLKFWVGDLAKFHVLFLLFVALMF
FVSLMFLFGYHCWLVAKNRSTLEAFSPPVFQNGPDRNGFNVGLSKNLRQV
FGEHKKLWFIPVFTSQGDGHYFPLRTLRESE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6bms Chain A Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6bms Fatty acyl recognition and transfer by an integral membraneS-acyltransferase.
Resolution2.441 Å
Binding residue
(original residue number in PDB)		C115 C118 H128 C135
Binding residue
(residue number reindexed from 1)		C112 C115 H125 C132
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.225: protein S-acyltransferase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0016409 palmitoyltransferase activity
GO:0016746 acyltransferase activity
GO:0019705 protein-cysteine S-myristoyltransferase activity
GO:0019706 protein-cysteine S-palmitoyltransferase activity
GO:0046872 metal ion binding
GO:0140439 protein-cysteine S-stearoyltransferase activity
Biological Process
GO:0018230 peptidyl-L-cysteine S-palmitoylation
GO:0072657 protein localization to membrane
GO:0140450 protein targeting to Golgi apparatus
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0045202 synapse

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6bms, PDBe:6bms, PDBj:6bms
PDBsum6bms
PubMed29326245
UniProtF1QXD3|ZH15B_DANRE Palmitoyltransferase ZDHHC15B (Gene Name=zdhhc15b)

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