Structure of PDB 6bin Chain A Binding Site BS01
Receptor Information
>6bin Chain A (length=179) Species:
9606
(Homo sapiens) [
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EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFA
SFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP
NVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLP
FLPSTEDVYDCRVEHWGLDEPLLKHWEFD
Ligand information
>6bin Chain C (length=13) Species:
9606
(Homo sapiens) [
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QYMtADQAAGGLR
Receptor-Ligand Complex Structure
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PDB
6bin
The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.
Resolution
2.50001 Å
Binding residue
(original residue number in PDB)
Q9 A52 S53 F54 N62 N69 I72
Binding residue
(residue number reindexed from 1)
Q7 A50 S51 F52 N60 N67 I70
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0006955
immune response
GO:0019882
antigen processing and presentation
Cellular Component
GO:0016020
membrane
GO:0042613
MHC class II protein complex
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Biological Process
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Cellular Component
External links
PDB
RCSB:6bin
,
PDBe:6bin
,
PDBj:6bin
PDBsum
6bin
PubMed
29317506
UniProt
P01903
|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)
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