Structure of PDB 6bha Chain A Binding Site BS01
Receptor Information
>6bha Chain A (length=146) Species:
9606
(Homo sapiens) [
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SGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETF
RNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIF
GTNGPVDLKKITNFFRGDRCRSLVGKPKLFIIQACRGTELDCGIET
Ligand information
>6bha Chain C (length=4) Species:
9606
(Homo sapiens) [
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DEVD
Receptor-Ligand Complex Structure
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PDB
6bha
Modifications to a common phosphorylation network provide individualized control in caspases.
Resolution
1.603 Å
Binding residue
(original residue number in PDB)
R64 H121 C163
Binding residue
(residue number reindexed from 1)
R36 H93 C135
Enzymatic activity
Enzyme Commision number
3.4.22.56
: caspase-3.
Gene Ontology
Molecular Function
GO:0004197
cysteine-type endopeptidase activity
GO:0008234
cysteine-type peptidase activity
Biological Process
GO:0006508
proteolysis
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Molecular Function
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Biological Process
External links
PDB
RCSB:6bha
,
PDBe:6bha
,
PDBj:6bha
PDBsum
6bha
PubMed
29414778
UniProt
P42574
|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)
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