Structure of PDB 6bh9 Chain A Binding Site BS01

Receptor Information
>6bh9 Chain A (length=146) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETF
RNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIF
GTNGPVDLKKITNFFRGDRCRSLAGKPKLFIIQACRGTELDCGIET
Ligand information
Receptor-Ligand Complex Structure
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PDB6bh9 Modifications to a common phosphorylation network provide individualized control in caspases.
Resolution1.94 Å
Binding residue
(original residue number in PDB)		R64 H121 C163
Binding residue
(residue number reindexed from 1)		R36 H93 C135
Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6bh9, PDBe:6bh9, PDBj:6bh9
PDBsum6bh9
PubMed29414778
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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