Structure of PDB 6b4e Chain A Binding Site BS01

Receptor Information
>6b4e Chain A (length=296) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTNFDKISKMFWHYKDKIAQIKQDIVLPIKKADVNVRNLLSRHKRKINPK
FGQLTNSNQQLFKIQNELTQLINDTKGDSLAYHWILNFIAKAVVHQAETE
VRVKPESALPLGKLTLYLLVQFPELQELFMARLVKKCPFVIGFTCEIDTE
KGRQNMGWKRNNENKWEDNTSYDERMGGILSLFAIITRLQLPQEFITTTS
HPFPIALSWHILARICNTPLNLITNTHFVILGSWWDAAAVQFLQAYGNQA
SKLLILIGEELTSRMAEKKYVGAARLRILLEAWQNNNMESFPEMSP
Ligand information
Ligand IDPRO
InChIInChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1
InChIKeyONIBWKKTOPOVIA-BYPYZUCNSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C1C[C@H](NC1)C(=O)O
CACTVS 3.341OC(=O)[C@@H]1CCCN1
CACTVS 3.341OC(=O)[CH]1CCCN1
OpenEye OEToolkits 1.5.0C1CC(NC1)C(=O)O
ACDLabs 10.04O=C(O)C1NCCC1
FormulaC5 H9 N O2
NamePROLINE
ChEMBLCHEMBL54922
DrugBankDB00172
ZINCZINC000000895360
PDB chain6b4e Chain A Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6b4e Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		I271 R279 L282 S283 W326
Binding residue
(residue number reindexed from 1)		I29 R37 L40 S41 W84
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0016973 poly(A)+ mRNA export from nucleus
Cellular Component
GO:0005643 nuclear pore

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Biological Process
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Cellular Component
External links
PDB RCSB:6b4e, PDBe:6b4e, PDBj:6b4e
PDBsum6b4e
PubMed29899397
UniProtQ12315|GLE1_YEAST mRNA export factor GLE1 (Gene Name=GLE1)

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