Structure of PDB 6b45 Chain A Binding Site BS01

Receptor Information
>6b45 Chain A (length=424) Species: 208963 (Pseudomonas aeruginosa UCBPP-PA14) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QELRQFIESFIQERLQGKLDKLQPDEDDKRQTLLATHRREAWLADAARRV
GQLQLVTHTLKPIHPDARGSNLHSLPQAPGQPGLAGSHELGDRLVSDVVG
NAAALDVFKFLSLQYQGKNLLNWLTEDSAEALQALSDNAEQAREWRQAFI
GITTVKGAPASHSLAKQLYFPLPGSGYHLLAPLFPTSLVHHVHALLREAR
FGDAAKAAREARSRQESWPHGFSEYPNLAIQKFGGTKPQNISQLNNERRG
ENWLLPSLPPNWQRQNVNAPMRHSSVFEHDFGRTPEVSRLTRTLQRFLAK
TVHNNLAIRQRRAQLVAQICDEALQYAARLRELEPGWSATPGCQLHDAEQ
LWLDPLRAQTDETFLQRRLRGDWPAEVGNRFANWLNRAVSSDSQILGSPE
AAQWSQELSKELTMFKEILEDERD
Ligand information
>6b45 Chain M (length=60) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cuaagaaauucacggcgggcuugauguccgcgucuaccugguucacugcc
guguaggcag
..................................................
..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6b45 Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		S173 K176 Q177 L178 Y179 Y187 L193
Binding residue
(residue number reindexed from 1)		S163 K166 Q167 L168 Y169 Y177 L183
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0051607 defense response to virus

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6b45, PDBe:6b45, PDBj:6b45
PDBsum6b45
PubMed28985564
UniProtQ02ML9|CSY1_PSEAB CRISPR-associated protein Csy1 (Gene Name=csy1)

[Back to BioLiP]