Structure of PDB 6b3x Chain A Binding Site BS01

Receptor Information
>6b3x Chain A (length=327) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EFGIDLEFQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADAS
IKILDTERMLANHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLF
DYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQ
CFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTF
EKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLS
GRQVHRTQAVFNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIV
RCIVHSPTNPGFMTCSDDFRARFWYRR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6b3x Reconstitution of the CstF complex unveils a regulatory role for CstF-50 in recognition of 3'-end processing signals.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		A217 H226 P227 F231 C251 F252 V253 S273 V292 S293 N294
Binding residue
(residue number reindexed from 1)		A117 H126 P127 F131 C151 F152 V153 S173 V192 S193 N194
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0031124 mRNA 3'-end processing
Cellular Component
GO:0005848 mRNA cleavage stimulating factor complex

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Biological Process
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Cellular Component
External links
PDB RCSB:6b3x, PDBe:6b3x, PDBj:6b3x
PDBsum6b3x
PubMed29186539
UniProtQ05048|CSTF1_HUMAN Cleavage stimulation factor subunit 1 (Gene Name=CSTF1)

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