Structure of PDB 6at9 Chain A Binding Site BS01

Receptor Information
>6at9 Chain A (length=274) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQKMEPRAP
WIEQEGPEYWDQETRNMKAHSQTDRANLGTLRGYYNQSEDGSHTIQIMYG
CDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAV
HAAEQRRVYLEGRCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRW
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6at9 A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations.
Resolution2.9503 Å
Binding residue
(original residue number in PDB)
Y7 E63 N66 M67 H70 T73 N77 L81 Y84 Y99 R114 D116 T143 K146 W147 A152 R156 Y159 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 N66 M67 H70 T73 N77 L81 Y84 Y99 R114 D116 T143 K146 W147 A152 R156 Y159 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6at9, PDBe:6at9, PDBj:6at9
PDBsum6at9
PubMed29441070
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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