Structure of PDB 6at5 Chain A Binding Site BS01

Receptor Information
>6at5 Chain A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAP
WIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYG
CDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAA
REAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6at5 Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide.
Resolution1.5 Å
Binding residue
(original residue number in PDB)
Y7 N63 I66 Y67 S77 Y84 Y99 Y123 T143 W147 E152 Q155 R156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 N63 I66 Y67 S77 Y84 Y99 Y123 T143 W147 E152 Q155 R156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation

View graph for
Biological Process
External links
PDB RCSB:6at5, PDBe:6at5, PDBj:6at5
PDBsum6at5
PubMed29531227
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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