Structure of PDB 6ar2 Chain A Binding Site BS01
Receptor Information
>6ar2 Chain A (length=134) Species:
9606
(Homo sapiens) [
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PSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVL
SRNHALVWFDHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGD
IIQFGVDVTENTRKVTHGCIVSTIKLFLPDGMEA
Ligand information
>6ar2 Chain C (length=6) Species:
9606
(Homo sapiens) [
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DGTMKR
Receptor-Ligand Complex Structure
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PDB
6ar2
SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.
Resolution
1.55 Å
Binding residue
(original residue number in PDB)
R32 K49 V50 L51 S52 R53 S75 N76 V107 D108 V109 E111 H118
Binding residue
(residue number reindexed from 1)
R31 K48 V49 L50 S51 R52 S74 N75 V106 D107 V108 E110 H117
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6ar2
,
PDBe:6ar2
,
PDBj:6ar2
PDBsum
6ar2
PubMed
29063833
UniProt
Q14BN4
|SLMAP_HUMAN Sarcolemmal membrane-associated protein (Gene Name=SLMAP)
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