Structure of PDB 6aaf Chain A Binding Site BS01
Receptor Information
>6aaf Chain A (length=112) Species:
284812
(Schizosaccharomyces pombe 972h-) [
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RSQFKDDFSFEKRKTESQRIREKYPDRIPVICEKVDKSDIAAIDKKKYLV
PSDLTVGQFVYVIRKRIKLSPEKAIFIFIDEILPPTAALMSTIYEEHKSE
DGFLYITYSGEN
Ligand information
>6aaf Chain B (length=22) Species:
284812
(Schizosaccharomyces pombe 972h-) [
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LQFEIDDEMEPLYNQAKQMRYG
Receptor-Ligand Complex Structure
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PDB
6aaf
Lipidation-independent vacuolar functions of Atg8 rely on its noncanonical interaction with a vacuole membrane protein
Resolution
2.197 Å
Binding residue
(original residue number in PDB)
F5 F9 E17 I21 Y25 R28 K46 K48 Y49 P52 Q59 Y62 V63 R67 F104
Binding residue
(residue number reindexed from 1)
F4 F8 E16 I20 Y24 R27 K45 K47 Y48 P51 Q58 Y61 V62 R66 F103
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0005515
protein binding
GO:0008429
phosphatidylethanolamine binding
Biological Process
GO:0000045
autophagosome assembly
GO:0000422
autophagy of mitochondrion
GO:0006914
autophagy
GO:0006995
cellular response to nitrogen starvation
GO:0007033
vacuole organization
GO:0015031
protein transport
GO:0016236
macroautophagy
GO:0061025
membrane fusion
GO:0097352
autophagosome maturation
Cellular Component
GO:0000324
fungal-type vacuole
GO:0000329
fungal-type vacuole membrane
GO:0000407
phagophore assembly site
GO:0000421
autophagosome membrane
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0005773
vacuole
GO:0005829
cytosol
GO:0016020
membrane
GO:0031410
cytoplasmic vesicle
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:6aaf
,
PDBe:6aaf
,
PDBj:6aaf
PDBsum
6aaf
PubMed
30451685
UniProt
O94272
|ATG8_SCHPO Autophagy-related protein 8 (Gene Name=atg8)
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