Structure of PDB 6a9u Chain A Binding Site BS01

Receptor Information

>6a9u Chain A (length=405) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GELTPGISALEYYERRIRLAETLPPKSCVILAGNDIQYPFQQENDLFYLS
GWNEPNSVMILEKPTDSLSDTIFHMLVPPFRSGVYGVQEIFNADESASIN
DLSKYLPKIINRNEFIYFDMLSSSNFKHIKSLLDNKTIKPISKRIAEFRK
IKSPQELRIMRRAGQISGRSFNQAFAKRFRNERTLDSFLHYKFISGGCDK
DAYIPVVATGSNSLCIHYTRNDDVMFDDEMVLVDAAGSLGGYCADISRTW
PNSGKFTDAQRDLYEAVLNVQRDCIKLCKASNNYSLHDIHEKSITLMKQE
LKNLGIDKVSGWNVEKLYPHYIGHNLGLDVHDVPKVSRYEPLKVGQVITI
EPGLYIPNEESFPSYFRNVGIRIEDDIAIGEDTYTNLTVEAVKEIDDLEN
VMQNG

Ligand information

>6a9u Chain B (length=4) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

tPPA

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6a9u Crystal structures and biochemical analyses of intermediate cleavage peptidase: role of dynamics in enzymatic function.
Resolution	2.4 Å
Binding residue (original residue number in PDB)	Y296 D327 D338 H417 E444 E467
Binding residue (residue number reindexed from 1)	Y203 D234 D245 H324 E351 E374

Enzymatic activity

Enzyme Commision number

3.4.11.26: intermediate cleaving peptidase 55.

Gene Ontology

	Molecular Function
GO:0030145	manganese ion binding
GO:0070006	metalloaminopeptidase activity

View graph for
Molecular Function

External links

PDB	RCSB:6a9u, PDBe:6a9u, PDBj:6a9u
PDBsum	6a9u
PubMed	30582634
UniProt	P40051\|ICP55_YEAST Intermediate cleaving peptidase 55 (Gene Name=ICP55)

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