Structure of PDB 6a7w Chain A Binding Site BS01

Receptor Information
>6a7w Chain A (length=324) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TDTIYHAKDAVQTTKPSERKPRLVVFVVGETARADHVQFNGYGRETFPQL
AKVDGLANFSQVTSCGTSTAYSVPCMFSYLGQDDYDVDTAKYQENVLDTL
DRLGVGILWRDNNSDSKGVMDKLPATQYFDYKSATNNTICNTNPYNECRD
VGMLVGLDDYVSANNGKDMLIMLHQMGNHGPAYFKRYDEQFAKFTPVCEG
NELAKCEHQSLINAYDNALLATDDFIAKSIDWLKTHEANYDVAMLYVSDH
GESLGENGVYLHGMPNAFAPKEQRAVPAFFWSNNTTFKPTASDTVLTHDA
ITPTLLKLFDVTAGKVKDRAAFIQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6a7w Chain A Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6a7w Structural and functional insights into MCR-2 mediated colistin resistance.
Resolution2.988 Å
Binding residue
(original residue number in PDB)		E244 T283 D463 H464
Binding residue
(residue number reindexed from 1)		E30 T69 D249 H250
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016772 transferase activity, transferring phosphorus-containing groups

View graph for
Molecular Function
External links
PDB RCSB:6a7w, PDBe:6a7w, PDBj:6a7w
PDBsum6a7w
PubMed30194678
UniProtA0A1C3NEV1

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