Structure of PDB 6a30 Chain A Binding Site BS01

Receptor Information
>6a30 Chain A (length=527) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ERFVKLLDQLHNSLRIDLSMYRNNFPASSPERLQDLKSTVDLLTSITFFR
MKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHELYGREYQTEEQGP
SIKNLDFWSKLITLIVSIIEEDKNSYTPCLNQFPQELNVGKISAEVMWSL
FAQDMKYAMEEHDKHRLCKSADYMNLHFKVKWLYNEYVAELPTFKDRVPE
YPAWFEPFVIQWLDENEEVSRDFLHGALERDKKDGFQQTSEHALFSCSVV
DVFSQLNQSFEIIKKLECPDPQIVGHYMRRFAKTISNVLLQYADIVSKDF
ASYCSKEKEKVPCILMNNTQQLRVQLEKMFEAMGGKELDAEASGTLKELQ
VKLNNVLDELSHVFATSFQPHIEECVRQMGDILSQVKGTGNVPASACSSV
AQDADNVLQPIMDLLDSNLTLFAKICEKTVLKRVLKELWKLVMNTMERTI
VLPPEFSKLKDHMVREEAKSLTPKQCAVVELALDTIKQYFHAGGVGLKKT
FLEKSPDLQSLRYALSLYTQATDLLIK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6a30 Munc18 and Munc13 serve as a functional template to orchestrate neuronal SNARE complex assembly.
Resolution2.793 Å
Binding residue
(original residue number in PDB)
L1372 T1373 Y1442 A1445
Binding residue
(residue number reindexed from 1)
L419 T420 Y489 A492
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0019992 diacylglycerol binding
Biological Process
GO:0007268 chemical synaptic transmission

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Molecular Function

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Biological Process
External links
PDB RCSB:6a30, PDBe:6a30, PDBj:6a30
PDBsum6a30
PubMed30622273
UniProtQ62768|UN13A_RAT Protein unc-13 homolog A (Gene Name=Unc13a)

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