Structure of PDB 6a0f Chain A Binding Site BS01

Receptor Information
>6a0f Chain A (length=302) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLLVEGRRVRLPQSAGDLVRAHPPLEERARLLRGQSVQQVGPQGLLYVQQ
RELAVTSPKDGSISILGSDDATTSHIVVLRHTGNGATCLTHCDGTDTKAE
VPLIMNSIKSFSDQCGRLEVHLVGGFSDDRQLSQKLTHQLLSEFDRQEDD
IHLVTLCVTELNDREENENHFPVIYGIAVNIKTAEIYRASFQDRGPEEQL
RAARTLAGGPMISIYDAETEQLRIGPYSWTPFPHVDFWLHQDDKQILENL
STSPLAEPPHFVEHIRSTLMFLKKHPSPAHTLFSGNKALLYKKNEDGLWE
KI
Ligand information
Receptor-Ligand Complex Structure
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PDB6a0f Structural Analyses on the Deamidation of N-Terminal Asn in the Human N-Degron Pathway.
Resolution2.384 Å
Binding residue
(original residue number in PDB)		Q51 T73 T74 S75 L253 S254 T255 E260 I268
Binding residue
(residue number reindexed from 1)		Q50 T72 T73 S74 L250 S251 T252 E257 I265
Enzymatic activity
Enzyme Commision number 3.5.1.121: protein N-terminal asparagine amidohydrolase.
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008418 protein-N-terminal asparagine amidohydrolase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007613 memory
GO:0008344 adult locomotory behavior
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6a0f, PDBe:6a0f, PDBj:6a0f
PDBsum6a0f
PubMed31968674
UniProtQ96AB6|NTAN1_HUMAN Protein N-terminal asparagine amidohydrolase (Gene Name=NTAN1)

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