Structure of PDB 5zzu Chain A Binding Site BS01

Receptor Information
>5zzu Chain A (length=353) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALPPLANFKDESGNEPRTLVLVIGESTQRGRMSLYGYPRETTPELDALHK
TDPNLTVFNNVVTSRPYTIEILQQALTFANEKNPDLYLTQPSLMNMMKQA
GYKTFWITNQQTMTARNTMLTVFSRQTDKQYYMNQQAREYDTNVLKPFQE
VLNDPAPKKLIIVHLLGTHIKYKYRYPENQGKFDGNTDHVPPGLNAEELE
SYNDYDNANLYNDHVVASLIKDFKAANPNGFLVYFSDHGEEVYDTPPHKT
QGRNEDNPTRHMYTIPFLLWTSEKWQATHPRDFSQDVDRKYSLAELIHTW
SDLAGLSYDGYDPTRSVVNPQFKETTRWIGNPYKKNALIDYDTLPYGDQV
GNQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5zzu Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5zzu Structural and mechanistic insights into polymyxin resistance mediated by EptC originating from Escherichia coli
Resolution2.1 Å
Binding residue
(original residue number in PDB)		Q294 T297 A299
Binding residue
(residue number reindexed from 1)		Q74 T77 A79
Annotation score4
Enzymatic activity
Enzyme Commision number 2.7.-.-
Gene Ontology
Molecular Function
GO:0016772 transferase activity, transferring phosphorus-containing groups

View graph for
Molecular Function
External links
PDB RCSB:5zzu, PDBe:5zzu, PDBj:5zzu
PDBsum5zzu
PubMed
UniProtP0CB39|EPTC_ECOLI Phosphoethanolamine transferase EptC (Gene Name=eptC)

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