Structure of PDB 5zyw Chain A Binding Site BS01

Receptor Information
>5zyw Chain A (length=233) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QNWFPIFNPERSDKPSVPLKIPLQRNVIPSVTRVLQQTMTKQQVFLLERW
KQRMILELGEDGFKEYTSNVFLQGKRFHEALESILSPNLLKSGYIESVQH
ILKDVSGVRALESAVQHETLNYIGLLDCVAEYQGKLCVIDWKTSEKPKPF
IQSTFDNPLQVVAYMGAMNHDTNYSFQVQCGLIVVAYKDGSPAHPHFMDA
ELCSQYWTKWLLRLEEYTEKKKNQNIQKPEYSE
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain5zyw Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5zyw Structural insights into DNA degradation by human mitochondrial nuclease MGME1
Resolution2.2 Å
Binding residue
(original residue number in PDB)		D238 E344
Binding residue
(residue number reindexed from 1)		D127 E233
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
External links
PDB RCSB:5zyw, PDBe:5zyw, PDBj:5zyw
PDBsum5zyw
PubMed30247721
UniProtQ9BQP7|MGME1_HUMAN Mitochondrial genome maintenance exonuclease 1 (Gene Name=MGME1)

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