Structure of PDB 5zwi Chain A Binding Site BS01
Receptor Information
>5zwi Chain A (length=240) Species:
10116
(Rattus norvegicus) [
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KLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMSPLSMLPHLADLV
SYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDM
SWDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLM
AICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMI
QKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGN
Ligand information
>5zwi Chain C (length=11) Species:
9606
(Homo sapiens) [
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KNHPMLMNLLK
Receptor-Ligand Complex Structure
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PDB
5zwi
Identification of the Histidine Residue in Vitamin D Receptor That Covalently Binds to Electrophilic Ligands
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
I238 K242 Q255 I256 L259 K260 P412 E416
Binding residue
(residue number reindexed from 1)
I58 K62 Q75 I76 L79 K80 P232 E236
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0004879
nuclear receptor activity
Biological Process
GO:0006355
regulation of DNA-templated transcription
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Molecular Function
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Biological Process
External links
PDB
RCSB:5zwi
,
PDBe:5zwi
,
PDBj:5zwi
PDBsum
5zwi
PubMed
29936834
UniProt
P13053
|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)
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